Tatiana Foroud, Ph.D.
P. Michael Conneally Professor of Medical and Molecular Genetics
Director of Hereditary Genomics Division
- B.S. 1987 - Fairfield University
- M.S. 1989 - The University of California, Los Angeles
- Ph.D. 1994 - Indiana University School of Medicine
The central focus of research in Dr. Foroud’s laboratory is the identification of genes contributing to disease. Ongoing studies are focusing on a variety of disorders including Parkinson disease, Alzheimer disease, intracranial aneurysms, alcohol dependence, and cancer. The tools that are currently being employed for gene identification include the genomewide association approach which evaluates millions of SNPs throughout the genome to identify relatively common variants contributing to disease susceptibility. Another approach being utilized with increasing frequency is sequencing – currently of the exome – to identify rare variants that have large effects on disease risk. Dr. Foroud’s research group utilizes statistical approaches to analyze the large amounts of data being generated.
Dr. Foroud also teaches two of the courses in the Hereditary Genomics Division: Q628: Fundamentals of Population Genetics and Q630: Population Genetics.
Foroud T, FIA Study Investigators. Whole exome sequencing of intracranial aneurysm. Stroke 2013;44(6 Suppl 1):S26-S28.
Suttie M, Foroud T, Wetherill L, Jacobson JL, Molteno CD, Meintjes EM, Hoyme HE, Khaole N, Robinson LK, Riley EP, Jacobson SW, Hammond P. Facial dysmorphism across the fetal alcohol spectrum. Pediatrics 2013; 131(3):e779-88.
Farlow JL and Foroud T. The Genetics of Dementia. Seminars in Neurology 2013;33(4):417-422.
Callahan CM, Foroud T, Saykin AJ, Shekhar A, Hendrie HC. Translational Research on Aging: Clinical epidemiology as a bridge between the sciences. Translational Research 2014;163(5):439-445.
Farlow J, Pankratz ND, Wojcieszek J, Foroud T. Parkinson Disease Overview. 2004 May 25 [Updated 2014 Feb 27]. In: Pagon RA, Adam MP, Bird TD, et al., editors. GeneReviews(r) [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2014. Available from: http://www.ncbi.nlm.nih.gov/books/NBK1223/.
Wetherill L, Agrawal A, Kapoor M, Bertelsen S, Bierut LJ, Brooks A, Dick D, Hesselbrock M, Hesselbrock V, Koller DL, Le N, Nurnberger JI, Salvatore JE, Schuckit M, Tischfield JA, Wang JC, Xuei X, Edenberg HJ, Porjesz B, Bucholz K, Goate AM, Foroud T. Association of substance dependence phenotypes in the COGA sample. Addiction Biology 2014. doi:10.1111/adb.12153. [Epub ahead of print]
Alam I, Koller DL, Canete T, Blazquez G, Lopez-Aumatell R, Martinez-Membrives E, Diaz-Moran S, Tobena A, Fernanedez-Teruel A, Stridh P, Diez M, Olsson T, Johannesson M, Baud A, Econs MJ, Foroud T. High-resolution genome screen for bone mineral density in heterogeneous stock rat. Journal of Bone and Mineral Research 2014. doi: 10.1002/jbmr.2195. [Epub ahead of print].